Dichloromethane → Methyl 5-fluoro-4-hydroxy-2-methoxybenzoate

HRID 2140467Notes

Reaction equation

HRID 2140467 reaction equation
[Cl:22][c:23]1[cH:24][n+:25]([F:26])[cH:27][c:28]([Cl:29])[cH:30]1.[Cl:31][CH2:32][Cl:33].[OH:1][c:2]1[cH:3][c:4]([O:12][CH3:13])[c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][cH:11]1.[S:14]([O-:15])([C:16]([F:17])([F:18])[F:19])(=[O:20])=[O:21]>>[OH:1][c:2]1[cH:3][c:4]([O:12][CH3:13])[c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][c:11]1[F:18]

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 27245793,5-Dichloro-1-fluoropyridin-1-iumHCID 2758875TrifluoromethanesulfonateHCID 12532676Methyl 4-hydroxy-2-methoxybenzoate

Product 1

HCID 18914108Methyl 5-fluoro-4-hydroxy-2-methoxybenzoate

Sources & evidence

ORD record
ord-c4f823af016a4dda822c2ef6284a69ab
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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