Methanol → 2-[4-[(3,4-dichloro-5-methyl-1H-pyrrole-2-carbonyl)amino]-3-ethoxypiperidin-1-yl]-4-(5-piperidin-1-ylpyrazin-2-yl)-1,3-thiazole-5-carboxylic acid
Reaction equation
[CH3:45][OH:46].[Cl:1][c:2]1[c:3]([C:9](=[O:10])[NH:11][CH:12]2[CH:13]([O:40][CH2:41][CH3:42])[CH2:14][N:15]([c:18]3[s:19][c:20]([C:35](=[O:36])[O:37][CH2:38][CH3:39])[c:21](-[c:23]4[n:24][cH:25][c:26]([N:29]5[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34]5)[n:27][cH:28]4)[n:22]3)[CH2:16][CH2:17]2)[nH:4][c:5]([CH3:8])[c:6]1[Cl:7].[Na+:44].[OH-:43]>>[Cl:1][c:2]1[c:3]([C:9](=[O:10])[NH:11][CH:12]2[CH:13]([O:40][CH2:41][CH3:42])[CH2:14][N:15]([c:18]3[s:19][c:20]([C:35](=[O:36])[OH:37])[c:21](-[c:23]4[n:24][cH:25][c:26]([N:29]5[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34]5)[n:27][cH:28]4)[n:22]3)[CH2:16][CH2:17]2)[nH:4][c:5]([CH3:8])[c:6]1[Cl:7]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-e76c822a23de4d38bd6f2469fbc30054
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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