2-Cyanophenylboronic acid → 5-Amino-4-cyano-3-(2'-cyano-biphenyl-4-yl)-thiophene-2-carboxylic acid ethyl ester
Reaction equation
[C:48]([c:49]1[cH:50][cH:51][cH:52][cH:53][c:54]1[B:55]([OH:56])[OH:57])#[N:58].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[s:7][c:8]([NH2:27])[c:9]([C:25]#[N:26])[c:10]1-[c:11]1[cH:12][cH:13][c:14](-[c:17]2[c:18]([S:23][CH3:24])[cH:19][cH:20][cH:21][cH:22]2)[cH:15][cH:16]1.[CH2:28]([O:29][C:30]([c:31]1[s:32][c:33]([NH2:34])[c:35]([C:45]#[N:46])[c:36]1-[c:37]1[cH:38][cH:39][c:40]([I:41])[cH:42][cH:43]1)=[O:44])[CH3:47]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[s:7][c:8]([NH2:27])[c:9]([C:25]#[N:26])[c:10]1-[c:11]1[cH:12][cH:13][c:14](-[c:17]2[c:18]([C:45]#[N:46])[cH:19][cH:20][cH:21][cH:22]2)[cH:15][cH:16]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-0fd6371f2dda40559baf0e668f72764d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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