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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2141019Generated: November 2, 2026

Dimethylformamide → 3-(2-{[(2,5-Dichloro-thiophene-3-carbonyl)-amino]-methyl}-4-hydroxy-phenyl)-propionic acid tert-butyl ester

https://huagongshe.com/reaction/2141019

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
Reactant4-MethylmorpholineHCID 7972—
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantIsobutyl chloroformateHCID 62365—
Reactant2,5-Dichlorothiophene-3-carboxylic acidHCID 225438—
ReactantTert-butyl-3-[2-(aminomethyl)-4-hydroxyphenyl]propanoateHCID 17984622—
Product3-(2-{[(2,5-Dichloro-thiophene-3-carbonyl)-amino]-methyl}-4-hydroxy-phenyl)-propionic acid tert-butyl esterHCID 58979103—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-bbdb2514a3b146c3921a1d41a420b17c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)