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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2141431Generated: October 26, 2026

Hydrochloric Acid → 4-[2-(4,4-Difluoro-piperidine-1-carbonyl)-1H-indol-5-yloxy]-piperidine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/2141431

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant(4,4-Difluoropiperidin-1-yl)[5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]methanoneHCID 11603838—
Reactant[5-(1-Cyclobutyl-piperidin-4-yloxy)-1-pyrimidin-5-yl-1H-indol-2-yl]-(4,4-difluoro-piperidin-1-yl)-methanoneHCID 16739661—
Reactant5-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]oxy-1H-indole-2-carboxylic acidHCID 67017923—
Product4-[2-(4,4-Difluoro-piperidine-1-carbonyl)-1H-indol-5-yloxy]-piperidine-1-carboxylic acid tert-butyl esterHCID 67017912—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-46f996a49306430595e9261b17b29d72
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)