4-(1-Aminoethyl)phenol → (+)-2-chloro-5-fluoro-N4-[1-(4-hydroxyphenyl)ethyl]-4-pyrimidineamine
Reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([Cl:8])[n:7]1.[OH:10][c:11]1[cH:12][cH:13][c:14]([CH:17]([CH3:18])[NH2:19])[cH:15][cH:16]1>>[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([NH:19][CH:17]([c:14]2[cH:13][cH:12][c:11]([OH:10])[cH:16][cH:15]2)[CH3:18])[n:7]1Participants
3
Sources & evidence
- ORD record
- ord-c099c116874e4aa0a24964600a2a831f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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