Acetate → 2-(4-Methoxyquinolin-6-yl)-1-(6-methylpyridin-2-yl)ethanone

HRID 2141972Notes

Reaction equation

HRID 2141972 reaction equation
[CH3:42][C:43]([CH3:44])([O-:45])[CH3:46].[CH3:48][c:49]1[cH:50][cH:51][cH:52][c:53]([C:55]([CH3:56])=[O:57])[n:54]1.[CH3:68][C:69](=[O:70])[OH:71].[CH:14]1([P:15]([CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21]2)[c:22]2[cH:23][cH:24][cH:25][cH:26][c:27]2-[c:28]2[cH:29][cH:30][cH:31][cH:32][c:33]2[N:34]([CH3:35])[CH3:36])[CH2:37][CH2:38][CH2:39][CH2:40][CH2:41]1.[Cl:1][c:2]1[cH:3][c:4]2[c:5]([O:12][CH3:13])[cH:6][cH:7][n:8][c:9]2[cH:10][cH:11]1.[K+:47].[O-:60][C:61]([CH3:62])=[O:63].[O-:64][C:65]([CH3:66])=[O:67].[OH2:58].[Pd+2:59]>>[c:2]1([CH2:56][C:55]([c:53]2[cH:52][cH:51][cH:50][c:49]([CH3:48])[n:54]2)=[O:57])[cH:3][c:4]2[c:5]([O:12][CH3:13])[cH:6][cH:7][n:8][c:9]2[cH:10][cH:11]1

Participants

10

Reactant 9

HCID 175Acetate2×HCID 176Acetic AcidHCID 813Potassium CationHCID 962WaterHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 1388722-Acetyl-6-methylpyridineHCID 27342172-(Dicyclohexylphosphino)-2'-(dimethylamino)biphenylHCID 45749132-Methylpropan-2-olateHCID 222886546-Chloro-4-methoxyquinoline

Product 1

HCID 222886552-(4-Methoxyquinolin-6-yl)-1-(6-methylpyridin-2-yl)ethanone

Sources & evidence

ORD record
ord-7c4f7617de564b72a1c2dfa838e76ce5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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