Methanol → Methyl 4,4-difluoro-1-[4-nitro-3-(trifluoromethyl)phenyl]pyrrolidine-2-carboxylate

HRID 2142039Notes

Reaction equation

HRID 2142039 reaction equation
[CH3:28][OH:29].[F:1][C:2]1([F:23])[CH2:3][CH:4]([C:20](=[O:21])[OH:22])[N:5]([c:7]2[cH:8][c:9]([C:16]([F:17])([F:18])[F:19])[c:10]([N+:13](=[O:14])[O-:15])[cH:11][cH:12]2)[CH2:6]1.[S:24]([Cl:25])([Cl:26])=[O:27]>>[F:1][C:2]1([F:23])[CH2:3][CH:4]([C:20](=[O:21])[O:22][CH3:28])[N:5]([c:7]2[cH:8][c:9]([C:16]([F:17])([F:18])[F:19])[c:10]([N+:13](=[O:14])[O-:15])[cH:11][cH:12]2)[CH2:6]1

Participants

4

Reactant 3

HCID 887MethanolHCID 24386Thionyl ChlorideHCID 68463527HCID 68463527, compound

Product 1

HCID 68463080Methyl 4,4-difluoro-1-[4-nitro-3-(trifluoromethyl)phenyl]pyrrolidine-2-carboxylate

Sources & evidence

ORD record
ord-48d5a29a48dd4b01bf07282d5cb573ca
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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