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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2142202Generated: October 27, 2026

Dimethylformamide → 3-chloro-1-(4-fluorophenyl)pyrazin-2(1H)-one

https://huagongshe.com/reaction/2142202

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantPhosphorus oxychlorideHCID 24813—
Reactant1-(4-fluorophenyl)-3-methoxypyrazin-2(1H)-oneHCID 22424345—
Product3-chloro-1-(4-fluorophenyl)pyrazin-2(1H)-oneHCID 67221416—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-b647200ef59b4ca6941d730283a5e4d1
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)