Dichloromethane → 2-(3-(Chloromethyl)-5-ethoxyphenoxy)-5-(trifluoromethyl)pyridine

HRID 214298Notes

Reaction equation

HRID 214298 reaction equation
[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6]([CH2:21][OH:22])[cH:7][c:8]([O:10][c:11]2[n:12][cH:13][c:14]([C:17]([F:18])([F:19])[F:20])[cH:15][cH:16]2)[cH:9]1.[Cl:27][CH2:28][Cl:29].[S:23]([Cl:24])([Cl:25])=[O:26]>>[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6]([CH2:21][Cl:25])[cH:7][c:8]([O:10][c:11]2[n:12][cH:13][c:14]([C:17]([F:18])([F:19])[F:20])[cH:15][cH:16]2)[cH:9]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 24386Thionyl ChlorideHCID 66876312(3-Ethoxy-5-(5-(trifluoromethyl)pyridin-2-yloxy)phenyl)methanol

Product 1

HCID 668756612-(3-(Chloromethyl)-5-ethoxyphenoxy)-5-(trifluoromethyl)pyridine

Sources & evidence

ORD record
ord-c284a2e303734271909808cd83755db5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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