Water → Methyl 2-{4-[2-(trifluoromethyl)phenoxy]piperidin-1-yl}-1,3-thiazole-5-carboxylate
Reaction equation
[Br:1][c:2]1[s:3][c:4]([C:7](=[O:8])[O:9][CH3:10])[cH:5][n:6]1.[F:11][C:12]([c:13]1[c:14]([O:15][CH:16]2[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]2)[cH:22][cH:23][cH:24][cH:25]1)([F:26])[F:27].[O:28]1[CH2:29][CH2:30][O:31][CH2:32][CH2:33]1.[OH2:34]>>[c:2]1([N:19]2[CH2:18][CH2:17][CH:16]([O:15][c:14]3[c:13]([C:12]([F:11])([F:26])[F:27])[cH:25][cH:24][cH:23][cH:22]3)[CH2:21][CH2:20]2)[s:3][c:4]([C:7](=[O:8])[O:9][CH3:10])[cH:5][n:6]1Participants
5
Sources & evidence
- ORD record
- ord-50e894c65f434422b339a5e52a4738f4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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