Potassium Cation → 2-[2-Fluoro-4-(1-hydroxy-1-methylethyl)phenyl]-5-{[6-(2-hydroxy-1-morpholin-4-ylethyl)pyridin-2-yl]amino}-1,3-thiazole-4-carboxamide
Reaction equation
[Br:21][c:22]1[cH:23][cH:24][cH:25][c:26]([CH:28]([CH2:29][OH:30])[N:31]2[CH2:32][CH2:33][O:34][CH2:35][CH2:36]2)[n:27]1.[C:37](=[O:38])([O-:39])[O-:40].[C:43]([OH:44])([CH2:45][CH3:46])([CH3:47])[CH3:48].[K+:41].[K+:42].[NH2:1][c:2]1[c:3]([C:18](=[O:19])[NH2:20])[n:4][c:5](-[c:7]2[c:8]([F:17])[cH:9][c:10]([C:13]([CH3:14])([CH3:15])[OH:16])[cH:11][cH:12]2)[s:6]1.[O:51]=[C:52]([CH:53]=[CH:54][c:55]1[cH:56][cH:57][cH:58][cH:59][cH:60]1)[CH:61]=[CH:62][c:63]1[cH:64][cH:65][cH:66][cH:67][cH:68]1.[O:69]=[C:70]([CH:71]=[CH:72][c:73]1[cH:74][cH:75][cH:76][cH:77][cH:78]1)[CH:79]=[CH:80][c:81]1[cH:82][cH:83][cH:84][cH:85][cH:86]1.[O:87]=[C:88]([CH:89]=[CH:90][c:91]1[cH:92][cH:93][cH:94][cH:95][cH:96]1)[CH:97]=[CH:98][c:99]1[cH:100][cH:101][cH:102][cH:103][cH:104]1.[Pd:49].[Pd:50]>>[NH:1]([c:2]1[c:3]([C:18](=[O:19])[NH2:20])[n:4][c:5](-[c:7]2[c:8]([F:17])[cH:9][c:10]([C:13]([CH3:14])([CH3:15])[OH:16])[cH:11][cH:12]2)[s:6]1)[c:22]1[cH:23][cH:24][cH:25][c:26]([CH:28]([CH2:29][OH:30])[N:31]2[CH2:32][CH2:33][O:34][CH2:35][CH2:36]2)[n:27]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-fefe7487ab7b47199804631940a9b379
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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