Dimethyl Sulfoxide → 6-bromo-N-((1,2-dihydro-4,6-dimethyl-2-oxopyridin-3-yl)methyl)-1-isopropyl-1H-indazole-4-carboxamide

HRID 2143855Notes

Reaction equation

HRID 2143855 reaction equation
[Br:3][c:4]1[cH:5][c:6]([C:16]([O:18][CH3:17])=[O:19])[c:7]2[cH:8][n:9][n:10]([CH:13]([CH3:14])[CH3:15])[c:11]2[cH:12]1.[CH3:31][CH2:32][OH:33].[CH3:34][S:35]([CH3:36])=[O:37].[NH2:20][CH2:21][c:22]1[c:23](=[O:30])[nH:24][c:25]([CH3:29])[cH:26][c:27]1[CH3:28].[Na+:2].[OH-:1]>>[Br:3][c:4]1[cH:5][c:6]([C:16](=[O:18])[NH:20][CH2:21][c:22]2[c:23](=[O:30])[nH:24][c:25]([CH3:29])[cH:26][c:27]2[CH3:28])[c:7]2[cH:8][n:9][n:10]([CH:13]([CH3:14])[CH3:15])[c:11]2[cH:12]1

Participants

7

Reactant 6

HCID 679Dimethyl SulfoxideHCID 702EthanolHCID 923Sodium ionHCID 961HydroxideHCID 70638443-(Aminomethyl)-4,6-dimethyl-1,2-dihydropyridin-2-oneHCID 67464993Methyl 6-bromo-1-isopropyl-1H-indazole-4-carboxylate

Product 1

HCID 545964906-bromo-N-((1,2-dihydro-4,6-dimethyl-2-oxopyridin-3-yl)methyl)-1-isopropyl-1H-indazole-4-carboxamide

Sources & evidence

ORD record
ord-15c03aeffc2c4d29a8a77258bba378cd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…