Trimethylacetamide → N-[4-[2-(hydroxymethyl)pyrrolidin-1-yl]-2-methylquinolin-7-yl]-2,2-dimethylpropanamide

HRID 2144031Notes

Reaction equation

HRID 2144031 reaction equation
[CH3:20][C:21]([C:22](=[O:23])[NH2:24])([CH3:25])[CH3:26].[I:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([N:13]3[CH:14]([CH2:18][OH:19])[CH2:15][CH2:16][CH2:17]3)[cH:7][c:8]([CH3:12])[n:9][c:10]2[cH:11]1>>[c:2]1([NH:24][C:22]([C:21]([CH3:20])([CH3:25])[CH3:26])=[O:23])[cH:3][cH:4][c:5]2[c:6]([N:13]3[CH:14]([CH2:18][OH:19])[CH2:15][CH2:16][CH2:17]3)[cH:7][c:8]([CH3:12])[n:9][c:10]2[cH:11]1

Participants

3

Reactant 2

HCID 12957TrimethylacetamideHCID 23433949[1-(7-Iodo-2-methylquinolin-4-yl)pyrrolidin-2-yl]methanol

Product 1

HCID 23433926N-[4-[2-(hydroxymethyl)pyrrolidin-1-yl]-2-methylquinolin-7-yl]-2,2-dimethylpropanamide

Sources & evidence

ORD record
ord-cbf694cba4ac4a28bfb5132e2cb58282
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…