HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2144078Generated: November 1, 2026
1,4-Dioxane → 1,1,1-Trifluoro-2-(2-(2-(1-propyn-1-yl)-4-(2-thiophenylsulfonyl)-1-piperazinyl)-5-pyrimidinyl)-2-propanol
https://huagongshe.com/reaction/2144078
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 3-(1-Propyn-1-yl)-1-(2-thiophenylsulfonyl)piperazine | HCID 66584007 | — |
| Reactant | 2-(2-Chloropyrimidin-5-yl)-1,1,1-trifluoropropan-2-ol | HCID 86670360 | — |
| Product | 1,1,1-Trifluoro-2-(2-(2-(1-propyn-1-yl)-4-(2-thiophenylsulfonyl)-1-piperazinyl)-5-pyrimidinyl)-2-propanol | HCID 66582439 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (4/10) |
|---|
| ORD ID | ord-19069e7039d947399a743f5436f0b549 |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (4/10) |
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