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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2144171Generated: October 31, 2026

2-Fluoro-5-(trifluoromethyl)phenyl isocyanate → 1-(4-(2-Amino-3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yloxy)naphthalen-1-yl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea

https://huagongshe.com/reaction/2144171

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-5-(trifluoromethyl)phenyl isocyanateHCID 2733380—
Reactant2-amino-8-(4-aminonaphthalen-1-yloxy)pyrido[2,3-b]pyrazin-3(4H)-oneHCID 46901095—
Product1-(4-(2-Amino-3-oxo-3,4-dihydropyrido[2,3-b]pyrazin-8-yloxy)naphthalen-1-yl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)ureaHCID 44134087—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-e5491ebceb2b4abfa24dc964afdd1a8a
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)