Sulfuryl chloride → 2-{2,5-bis(trifluoromethyl)phenyl}amino-5-chloro-3-cyclohexyl-6-trifluoromethyl-4(3H)-pyrimidinone
Reaction equation
[F:1][C:2]([c:3]1[c:4]([NH:13][c:14]2[n:15][c:16]([C:27]([F:28])([F:29])[F:30])[cH:17][c:18](=[O:26])[n:19]2[CH:20]2[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]2)[cH:5][c:6]([C:9]([F:10])([F:11])[F:12])[cH:7][cH:8]1)([F:31])[F:32].[S:33]([Cl:34])(=[O:35])([Cl:36])=[O:37]>>[F:1][C:2]([c:3]1[c:4]([NH:13][c:14]2[n:15][c:16]([C:27]([F:28])([F:29])[F:30])[c:17]([Cl:36])[c:18](=[O:26])[n:19]2[CH:20]2[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]2)[cH:5][c:6]([C:9]([F:10])([F:11])[F:12])[cH:7][cH:8]1)([F:31])[F:32]Participants
3
Sources & evidence
- ORD record
- ord-ac9002a782594207a7b5acdb7d88656e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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