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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2144452Generated: October 26, 2026

Water → 2-amino-5-[4-(difluoromethoxy)phenyl]-5-[3-(3-methoxyprop-1-yn-1-yl)phenyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one

https://huagongshe.com/reaction/2144452

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladiumHCID 23938—
ReactantPyrrolidineHCID 31268—
Reactant3-MethoxypropyneHCID 69393—
Reactant2-amino-4-(3-bromophenyl)-4-(4-(difluoromethoxy)phenyl)-1-methyl-1H-imidazol-5(4H)-oneHCID 59790307—
Product2-amino-5-[4-(difluoromethoxy)phenyl]-5-[3-(3-methoxyprop-1-yn-1-yl)phenyl]-3-methyl-3,5-dihydro-4H-imidazol-4-oneHCID 57435886—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-c14e6adf59d44b1ab2774898f5c7c792
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)