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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2144537Generated: October 25, 2026

Hydrochloric Acid → 7-((4-(4-chlorophenyl)piperidin-1-yl)methyl)-4-isopropyl-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-one

https://huagongshe.com/reaction/2144537

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantPropionitrileHCID 7854—
ReactantIodide IonHCID 30165—
ReactantDiisopropylethylamineHCID 81531—
Reactant4-(4-Chlorophenyl)piperidineHCID 1203613—
ReactantCyanomethyl(trimethyl)phosphaniumHCID 10514345—
Reactant7-(hydroxymethyl)-4-isopropyl-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-oneHCID 58324436—
Product7-((4-(4-chlorophenyl)piperidin-1-yl)methyl)-4-isopropyl-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-oneHCID 46864481—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-18a4db199d294a9da0bfa3b575f7f85c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)