Acetate → 8-(Benzyloxy)-2-(7-(2-methoxyethoxy)-imidazo[1,2-a]pyridin-3-yl)quinoline
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][cH:12][c:13]2[cH:14][cH:15][c:16]([Cl:19])[n:17][c:18]12.[CH3:20][O:21][CH2:22][CH2:23][O:24][c:25]1[cH:26][c:27]2[n:28]([cH:29][cH:30]1)[cH:31][cH:32][n:33]2.[Cl:47][CH2:48][Cl:49].[K+:34].[K+:35].[O-:128][C:129]([CH3:130])=[O:131].[O-:132][C:133]([CH3:134])=[O:135].[O-:36][C:37]([O-:38])=[O:39].[O:40]1[CH2:41][CH2:42][O:43][CH2:44][CH2:45]1.[OH2:46].[Pd+2:127].[cH:50]1[cH:51][cH:52][c:53]([P:54]([Pd:55]([P:56]([c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)([c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)[c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)([P:75]([c:76]2[cH:77][cH:78][cH:79][cH:80][cH:81]2)([c:82]2[cH:83][cH:84][cH:85][cH:86][cH:87]2)[c:88]2[cH:89][cH:90][cH:91][cH:92][cH:93]2)[P:94]([c:95]2[cH:96][cH:97][cH:98][cH:99][cH:100]2)([c:101]2[cH:102][cH:103][cH:104][cH:105][cH:106]2)[c:107]2[cH:108][cH:109][cH:110][cH:111][cH:112]2)([c:113]2[cH:114][cH:115][cH:116][cH:117][cH:118]2)[c:119]2[cH:120][cH:121][cH:122][cH:123][cH:124]2)[cH:125][cH:126]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][cH:11][cH:12][c:13]2[cH:14][cH:15][c:16](-[c:31]3[n:28]4[c:27]([cH:26][c:25]([O:24][CH2:23][CH2:22][O:21][CH3:20])[cH:30][cH:29]4)[n:33][cH:32]3)[n:17][c:18]12Participants
11
Reactant 10
HCID 175Acetate2×
HCID 813Potassium Cation2×
HCID 962Water
HCID 6344Dichloromethane
HCID 19660Carbonate Ion
HCID 312751,4-Dioxane
HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)
HCID 220422348-(Benzyloxy)-2-chloroquinoline
HCID 583692597-(2-Methoxyethoxy)imidazo[1,2-a]pyridine
HCID 178420554HCID 178420554, compoundProduct 1
Sources & evidence
- ORD record
- ord-8d9c65e922104ec9910e6b9c8dfbb5b6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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