Dimethyl Sulfoxide → [2-[5-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidin-7-yl]-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazin-7-yl]methanol

HRID 2145023Notes

Reaction equation

HRID 2145023 reaction equation
[CH2:17]1[CH:18]2[N:19]([CH2:20][CH2:21][NH:22]1)[CH2:23][CH:24]([CH2:27][OH:28])[CH2:25][CH2:26]2.[CH3:29][S:30]([CH3:31])=[O:32].[Cl:1][c:2]1[cH:3][c:4]2[n:5]([c:6]([NH2:8])[n:7]1)[n:9][c:10](-[c:12]1[o:13][cH:14][cH:15][cH:16]1)[n:11]2>>[c:2]1([N:22]2[CH2:17][CH:18]3[N:19]([CH2:20][CH2:21]2)[CH2:23][CH:24]([CH2:27][OH:28])[CH2:25][CH2:26]3)[cH:3][c:4]2[n:5]([c:6]([NH2:8])[n:7]1)[n:9][c:10](-[c:12]1[o:13][cH:14][cH:15][cH:16]1)[n:11]2

Participants

4

Reactant 3

HCID 679Dimethyl SulfoxideHCID 99427675-Amino-7-chloro-2-(2-furyl)[1,2,4]triazolo[1,5-c]pyrimidineHCID 12985539(Octahydro-1H-pyrido[1,2-A]pyrazin-7-YL)methanol

Product 1

HCID 11222433[2-[5-Amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidin-7-yl]-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazin-7-yl]methanol

Sources & evidence

ORD record
ord-bf901de4f7f94b69bb79131eb047e0e1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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