7-Benzyl-6-oxo-4-[4-(thiophene-2-carbonyl)-piperazin-1-yl]-6,7-dihydro-thieno[2,3-b]pyridine-5-carbonitrile → 7-Benzyl-3-methyl-6-oxo-4-[4-(thiophene-2-carbonyl)-piperazin-1-yl]-6,7-dihydro-thieno[2,3-b]pyridine-5-carbonitrile
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9]2[c:10]([c:11]([Cl:17])[c:12]([C:15]#[N:16])[c:13]1=[O:14])[c:18]([CH3:21])[cH:19][s:20]2.[CH2:22]([n:23]1[c:24](=[O:25])[c:26]([C:27]#[N:28])[c:29]([N:38]2[CH2:39][CH2:40][N:41]([C:44](=[O:45])[c:46]3[s:47][cH:48][cH:49][cH:50]3)[CH2:42][CH2:43]2)[c:30]2[cH:31][cH:32][s:33][c:34]12)[c:35]1[cH:36][cH:37][cH:51][cH:52][cH:53]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9]2[c:10]([c:11]([N:38]3[CH2:39][CH2:40][N:41]([C:44](=[O:45])[c:46]4[s:47][cH:48][cH:49][cH:50]4)[CH2:42][CH2:43]3)[c:12]([C:15]#[N:16])[c:13]1=[O:14])[c:18]([CH3:21])[cH:19][s:20]2Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-2ea1b17d238f46ed8dbe32be858e0037
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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