HCID 19931779, compound → HCID 53741367, compound

HRID 21452Notes

Reaction equation

HRID 21452 reaction equation
[CH:1]1([C:4](=[O:16])[CH2:5][C:6]([C:8]2[CH:13]=[CH:12][C:11]([S:14][CH3:15])=[CH:10][N:9]=2)=[O:7])[CH2:3][CH2:2]1.CC(C)C(O)=O.[CH3:23][N:24]([CH3:27])[CH:25]=O>O1CCOCC1>[CH:1]1([C:4](=[O:16])[C:5](=[CH:23][N:24]([CH3:27])[CH3:25])[C:6]([C:8]2[CH:13]=[CH:12][C:11]([S:14][CH3:15])=[CH:10][N:9]=2)=[O:7])[CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 19931779HCID 19931779, compoundHCID 53446501Dimethylformamide dimethyl acetate

Product 1

HCID 53741367HCID 53741367, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

A mixture of 3-cyclopropyl-1-[5-(methylsulphenyl)-pyrid-2-yl] propan-1,3-dione (2.9g), dimethylformamide dimethyl acetate and dioxane was stirred at room temperature overnight. It was evaporated to dryness and the residue was triturated with ether and filtered to give 3-cyclopropyl-2-(N,N-dimethylaminomethylene)-1-[5-(methylsulphenyl)-pyrid-2-yl ]propan-1,3-dione (3.24 g) as a brown solid which was used without further characterization.

Workup

  1. customIt was evaporated to dryness
  2. customthe residue was triturated with ether
  3. filtrationfiltered

Sources & evidence

ORD record
ord-5a32e2ced30949bd82cc8478df65c4c8
Source dataset
uspto-grants-1995_06
Patent number
US05424276

Reaction notes

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