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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2145511Generated: November 3, 2026

Tetrahydrofuran → 6-(4-chlorobenzoyl)-1-methyl-4-(3-((trimethylsilyl)ethynyl)phenyl)-1,8-naphthyridin-2(1H)-one

https://huagongshe.com/reaction/2145511

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
ReactantTrimethylsilylacetyleneHCID 66111—
Reactant4-(3-bromophenyl)-6-(4-chlorobenzoyl)-1-methyl-1,8-naphthyridin-2(1H)-oneHCID 70882515—
ReactantHCID 178420554HCID 178420554—
Product6-(4-chlorobenzoyl)-1-methyl-4-(3-((trimethylsilyl)ethynyl)phenyl)-1,8-naphthyridin-2(1H)-oneHCID 67428830—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-32a12d21543e47a09ab72ebf54ef76ff
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)