Acetate → 5-Chloro-4-methoxy-2-piperazin-1-ylaniline

HRID 2145624Notes

Reaction equation

HRID 2145624 reaction equation
[C:23]([O-:24])(=[O:25])[CH3:26].[C:28]([O-:29])(=[O:30])[CH3:31].[CH3:21][OH:22].[Cl:1][c:2]1[cH:3][c:4]([N+:16]([O-:17])=[O:18])[c:5]([N:10]2[CH2:11][CH2:12][NH:13][CH2:14][CH2:15]2)[cH:6][c:7]1[O:8][CH3:9].[H:19][H:20].[Pd+2:27]>>[Cl:1][c:2]1[cH:3][c:4]([NH2:16])[c:5]([N:10]2[CH2:11][CH2:12][NH:13][CH2:14][CH2:15]2)[cH:6][c:7]1[O:8][CH3:9]

Participants

6

Reactant 5

HCID 175Acetate2×HCID 887MethanolHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 684240111-(4-Chloro-5-methoxy-2-nitrophenyl)piperazineHCID 178418361HCID 178418361, compound

Product 1

HCID 578404075-Chloro-4-methoxy-2-piperazin-1-ylaniline

Sources & evidence

ORD record
ord-28fb09180a42432e895373235b2bdd28
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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