3-[3-(3-Chloro-5-fluorophenyl)-5-(1,3-thiazolidin-3-ylcarbonyl)furan-2-yl]benzenecarbonitrile → [5-(3-Chloro-4-fluorophenyl)-4-(3-chloro-5-fluorophenyl)furan-2-yl](1,3-thiazolidin-3-yl)methanone

HRID 2145704Notes

Reaction equation

HRID 2145704 reaction equation
[Cl:1][c:2]1[cH:3][c:4](-[c:5]2[cH:6][c:7]([C:8](=[O:9])[N:16]3[CH2:17][S:18][CH2:19][CH2:20]3)[o:10][c:11]2-[c:12]2[cH:13][c:14]([C:15]#[N:21])[cH:22][cH:23][cH:24]2)[cH:25][c:26]([F:27])[cH:28]1.[Cl:29][c:30]1[cH:31][c:32](-[c:37]2[c:38](-[c:45]3[cH:46][c:47]([Cl:52])[cH:48][c:49]([F:51])[cH:50]3)[cH:39][c:40]([C:42](=[O:43])[OH:44])[o:41]2)[cH:33][cH:34][c:35]1[F:36]>>[N:16]1([C:42]([c:40]2[cH:39][c:38](-[c:45]3[cH:46][c:47]([Cl:52])[cH:48][c:49]([F:51])[cH:50]3)[c:37](-[c:32]3[cH:31][c:30]([Cl:29])[c:35]([F:36])[cH:34][cH:33]3)[o:41]2)=[O:44])[CH2:17][S:18][CH2:19][CH2:20]1

Participants

3

Reactant 2

HCID 468323003-[3-(3-Chloro-5-fluorophenyl)-5-(1,3-thiazolidin-3-ylcarbonyl)furan-2-yl]benzenecarbonitrileHCID 580647965-(3-Chloro-4-fluorophenyl)-4-(3-chloro-5-fluorophenyl)furan-2-carboxylic acid

Product 1

HCID 46832583[5-(3-Chloro-4-fluorophenyl)-4-(3-chloro-5-fluorophenyl)furan-2-yl](1,3-thiazolidin-3-yl)methanone

Sources & evidence

ORD record
ord-497a29309c674f0982ad4e497203d298
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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