3,4-dimethoxy-N-methylaniline → N4-(3,4-Dimethoxy-phenyl)-2,N4-dimethyl-quinazoline-4,6-diamine

HRID 2145815Notes

Reaction equation

HRID 2145815 reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]([N:11]([c:12]2[n:13][c:14]([CH3:25])[n:15][c:16]3[cH:17][cH:18][c:19]([N+:22]([O-:23])=[O:24])[cH:20][c:21]23)[CH3:26])[cH:6][cH:7][c:8]1[O:9][CH3:10].[CH3:42][O:43][c:44]1[cH:45][c:46]([NH:47][CH3:48])[cH:49][cH:50][c:51]1[O:52][CH3:53].[Cl:27][c:28]1[c:29]2[c:30]([cH:31][cH:32][c:33]([N+:34]([O-:35])=[O:36])[cH:37]2)[n:38][c:39]([CH3:40])[n:41]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]([N:11]([c:12]2[n:13][c:14]([CH3:25])[n:15][c:16]3[cH:17][cH:18][c:19]([NH2:22])[cH:20][c:21]23)[CH3:26])[cH:6][cH:7][c:8]1[O:9][CH3:10]

Participants

4

Reactant 3

HCID 27869553,4-dimethoxy-N-methylanilineHCID 11653274(3,4-Dimethoxy-phenyl)-(2-methyl-6-nitro-quinazolin-4-yl)-methylamineHCID 249038664-Chloro-2-methyl-6-nitroquinazoline

Product 1

HCID 59242050N4-(3,4-Dimethoxy-phenyl)-2,N4-dimethyl-quinazoline-4,6-diamine

Sources & evidence

ORD record
ord-6e5c2452e9f9411aab7eff98ae38f4f3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…