Dichloromethane → 2-[4-(3-Aminopyrrolidin-1-yl)-7-methylquinazolin-2-yl]phenol

HRID 2146047Notes

Reaction equation

HRID 2146047 reaction equation
[Cl:32][CH2:33][Cl:34].[OH:1][c:2]1[c:3](-[c:8]2[n:9][c:10]3[cH:11][c:12]([CH3:31])[cH:13][cH:14][c:15]3[c:16]([N:18]3[CH2:19][CH:20]([NH:23][C:24](=[O:25])[O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[CH2:21][CH2:22]3)[n:17]2)[cH:4][cH:5][cH:6][cH:7]1>>[OH:1][c:2]1[c:3](-[c:8]2[n:9][c:10]3[cH:11][c:12]([CH3:31])[cH:13][cH:14][c:15]3[c:16]([N:18]3[CH2:19][CH:20]([NH2:23])[CH2:21][CH2:22]3)[n:17]2)[cH:4][cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 6344DichloromethaneHCID 136121483tert-butyl N-[1-[2-(2-hydroxyphenyl)-7-methylquinazolin-4-yl]pyrrolidin-3-yl]carbamate

Product 1

HCID 1361215132-[4-(3-Aminopyrrolidin-1-yl)-7-methylquinazolin-2-yl]phenol

Sources & evidence

ORD record
ord-59be9dd700b644749047035e25741495
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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