(6-Fluoro-5-methylpyridin-3-yl)boronic acid → [7-(6-Fluoro-5-methyl-pyridin-3-yl)-pyrrolo[2,1-f][1,2,4]triazin-2-yl]-(4-morpholin-4-yl-phenyl)-amine

HRID 2146258Notes

Reaction equation

HRID 2146258 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[cH:6][n:7][c:8]([NH:11][c:12]3[cH:13][cH:14][c:15]([N:18]4[CH2:19][CH2:20][O:21][CH2:22][CH2:23]4)[cH:16][cH:17]3)[n:9][n:10]12.[F:24][c:25]1[n:26][cH:27][c:28]([B:32]([OH:33])[OH:34])[cH:29][c:30]1[CH3:31]>>[c:2]1(-[c:28]2[cH:27][n:26][c:25]([F:24])[c:30]([CH3:31])[cH:29]2)[cH:3][cH:4][c:5]2[cH:6][n:7][c:8]([NH:11][c:12]3[cH:13][cH:14][c:15]([N:18]4[CH2:19][CH2:20][O:21][CH2:22][CH2:23]4)[cH:16][cH:17]3)[n:9][n:10]12

Participants

3

Reactant 2

HCID 17750247(6-Fluoro-5-methylpyridin-3-yl)boronic acidHCID 54578326(7-Bromo-pyrrolo[2,1-f][1,2,4]triazin-2-yl)-(4-morpholin-4-yl-phenyl)-amine

Product 1

HCID 66711982[7-(6-Fluoro-5-methyl-pyridin-3-yl)-pyrrolo[2,1-f][1,2,4]triazin-2-yl]-(4-morpholin-4-yl-phenyl)-amine

Sources & evidence

ORD record
ord-fe139946734446e8a503744d99a3ef3f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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