Dichloromethane → Propan-2-yl 4-amino-3-bromo-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)picolinate
Reaction equation
[Br:25][N:26]1[C:27](=[O:28])[CH2:29][CH2:30][C:31]1=[O:32].[Cl:33][CH2:34][Cl:35].[NH2:1][c:2]1[cH:3][c:4]([C:19](=[O:20])[O:21][CH:22]([CH3:23])[CH3:24])[n:5][c:6](-[c:9]2[c:10]([F:18])[c:11]([O:16][CH3:17])[c:12]([Cl:15])[cH:13][cH:14]2)[c:7]1[F:8]>>[NH2:1][c:2]1[c:3]([Br:25])[c:4]([C:19](=[O:20])[O:21][CH:22]([CH3:23])[CH3:24])[n:5][c:6](-[c:9]2[c:10]([F:18])[c:11]([O:16][CH3:17])[c:12]([Cl:15])[cH:13][cH:14]2)[c:7]1[F:8]Participants
4
Sources & evidence
- ORD record
- ord-e118c19cff59481293bbe7abc74199dd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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