3-Chloro-4-(3-fluorobenzyloxy)aniline → tert-Butyl 4-({3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}amino)-3-cyano-5,8-dihydrothieno[2,3-b:5,4-c']dipyridine-7(6H)-carboxylate

HRID 2146418Notes

Reaction equation

HRID 2146418 reaction equation
[Cl:18][c:19]1[c:20]2[c:21]([n:22][cH:23][c:24]1[C:25]#[N:26])[s:27][c:28]1[c:33]2[CH2:32][CH2:31][N:30]([C:34](=[O:35])[O:36][C:37]([CH3:38])([CH3:39])[CH3:40])[CH2:29]1.[Cl:1][c:2]1[cH:3][c:4]([NH2:5])[cH:6][cH:7][c:8]1[O:9][CH2:10][c:11]1[cH:12][c:13]([F:17])[cH:14][cH:15][cH:16]1>>[Cl:1][c:2]1[cH:3][c:4]([NH:5][c:19]2[c:20]3[c:21]([n:22][cH:23][c:24]2[C:25]#[N:26])[s:27][c:28]2[c:33]3[CH2:32][CH2:31][N:30]([C:34](=[O:35])[O:36][C:37]([CH3:38])([CH3:39])[CH3:40])[CH2:29]2)[cH:6][cH:7][c:8]1[O:9][CH2:10][c:11]1[cH:12][c:13]([F:17])[cH:14][cH:15][cH:16]1

Participants

3

Reactant 2

HCID 70592633-Chloro-4-(3-fluorobenzyloxy)anilineHCID 58116935tert-Butyl 4-chloro-3-cyano-5,8-dihydrothieno[2,3-b:5,4-c']dipyridine-7(6H)-carboxylate

Product 1

HCID 58116968tert-Butyl 4-({3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}amino)-3-cyano-5,8-dihydrothieno[2,3-b:5,4-c']dipyridine-7(6H)-carboxylate

Sources & evidence

ORD record
ord-2493b236e16d4d22a8a3e3167da2c915
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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