Methanol → 2-{1-[(Tert-butoxy)carbonyl]-4-hydroxypiperidin-4-yl}acetic acid

HRID 2146851Notes

Reaction equation

HRID 2146851 reaction equation
[C:3]([CH3:4])([CH3:5])([CH3:6])[O:7][C:8](=[O:9])[N:10]1[CH2:11][CH2:12][C:13]([OH:16])([CH2:17][C:18](=[O:19])[O:20][CH2:21][CH3:22])[CH2:14][CH2:15]1.[CH3:24][OH:25].[Na+:2].[OH-:1].[OH2:23]>>[C:3]([CH3:4])([CH3:5])([CH3:6])[O:7][C:8](=[O:9])[N:10]1[CH2:11][CH2:12][C:13]([OH:16])([CH2:17][C:18](=[O:19])[OH:20])[CH2:14][CH2:15]1

Participants

6

Reactant 5

HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 10469302Tert-butyl 4-(2-ethoxy-2-oxoethyl)-4-hydroxypiperidine-1-carboxylate

Product 1

HCID 100611062-{1-[(Tert-butoxy)carbonyl]-4-hydroxypiperidin-4-yl}acetic acid

Sources & evidence

ORD record
ord-6f961aff5f0448f3b0b3a97cb009f507
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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