Water → N-[2-amino-3-cyano-6-[3-(dimethylamino)pyrrolidin-1-yl]-4-methyl-5-phenylphenyl]-2,2-dimethylpropanamide
Reaction equation
[C:1]([C:2]([CH3:3])([CH3:4])[CH3:5])(=[O:6])[Cl:7].[CH:8]([Cl:9])([Cl:10])[Cl:11].[NH2:12][c:13]1[c:14]([C:35]#[N:36])[c:15]([CH3:34])[c:16](-[c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[c:17]([N:20]2[CH2:21][CH:22]([N:25]([CH3:26])[CH3:27])[CH2:23][CH2:24]2)[c:18]1[NH2:19].[OH2:37]>>[C:1]([C:2]([CH3:3])([CH3:4])[CH3:5])(=[O:6])[NH:19][c:18]1[c:13]([NH2:12])[c:14]([C:35]#[N:36])[c:15]([CH3:34])[c:16](-[c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[c:17]1[N:20]1[CH2:21][CH:22]([N:25]([CH3:26])[CH3:27])[CH2:23][CH2:24]1Participants
5
Sources & evidence
- ORD record
- ord-357d56cda1e242f4a946bde00d4e6721
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…