Diethyl Ether → Ganciclovir Impurity 43

HRID 2147095Notes

Reaction equation

HRID 2147095 reaction equation
[C:18]([O:19][CH2:20][O:21][CH:24]([CH2:25][O:26][CH2:27][c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)[CH2:34][O:35][CH2:36][c:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1)(=[O:22])[CH3:23].[C:1]([CH3:2])(=[O:3])[NH:4][c:5]1[nH:6][c:7](=[O:17])[c:8]2[n:9][cH:10][n:11]([C:14]([CH3:15])=[O:16])[c:12]2[n:13]1.[CH2:66]([O:67][CH2:68][CH3:69])[CH3:70].[N+:43]([c:44]1[cH:45][cH:46][c:47]([O:48][P:49]([O-:50])([O:51][c:52]2[cH:53][cH:54][c:55]([N+:56]([O-:57])=[O:58])[cH:59][cH:60]2)=[O:61])[cH:62][cH:63]1)([O-:64])=[O:65]>>[C:1]([CH3:2])(=[O:3])[NH:4][c:5]1[nH:6][c:7](=[O:17])[c:8]2[n:9][cH:10][n:11]([CH2:14][O:16][CH:24]([CH2:25][O:26][CH2:27][c:28]3[cH:29][cH:30][cH:31][cH:32][cH:33]3)[CH2:34][O:35][CH2:36][c:37]3[cH:38][cH:39][cH:40][cH:41][cH:42]3)[c:12]2[n:13]1

Participants

5

Reactant 4

HCID 3283Diethyl EtherHCID 5255575Bis(p-nitrophenyl)-phosphateHCID 11035330Ganciclovir Impurity 42HCID 1354335942,9-Diacetylguanine

Product 1

HCID 135545206Ganciclovir Impurity 43

Sources & evidence

ORD record
ord-b2b751edfe48421fa0b39dad8dcacc39
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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