1-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazine → (2-Benzyloxy-5-methanesulfonyl-phenyl)-[4-(3-fluoro-5-trifluoromethyl-pyridin-2-yl)-piperazin-1-yl]-methanone
Reaction equation
[CH2:18]([c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1)[O:25][c:26]1[c:27]([C:28](=[O:29])[OH:30])[cH:31][c:32]([S:35](=[O:36])(=[O:37])[CH3:38])[cH:33][cH:34]1.[F:1][c:2]1[c:3]([N:12]2[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]2)[n:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1>>[F:1][c:2]1[c:3]([N:12]2[CH2:13][CH2:14][N:15]([C:28]([c:27]3[c:26]([O:25][CH2:18][c:19]4[cH:20][cH:21][cH:22][cH:23][cH:24]4)[cH:34][cH:33][c:32]([S:35](=[O:36])(=[O:37])[CH3:38])[cH:31]3)=[O:29])[CH2:16][CH2:17]2)[n:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-f514c6b0cd9d4a39bad3b3ca2783d95a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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