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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2147213Generated: October 29, 2026

Bicarbonate Ion → 7-Propan-2-yl-2-[4-[2-[[1-[5-(trifluoromethyl)pyridin-2-yl]piperidin-4-yl]amino]ethyl]phenyl]-1,3-benzoxazole-5-carbonitrile

https://huagongshe.com/reaction/2147213

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantDimethylformamideHCID 6228—
ReactantDiisopropylethylamineHCID 81531—
Reactant1-(5-(Trifluoromethyl)pyridin-2-yl)piperidin-4-amineHCID 4778234—
Reactant2-[4-(2-Bromoethyl)phenyl]-7-propan-2-yl-1,3-benzoxazole-5-carbonitrileHCID 67140802—
Product7-Propan-2-yl-2-[4-[2-[[1-[5-(trifluoromethyl)pyridin-2-yl]piperidin-4-yl]amino]ethyl]phenyl]-1,3-benzoxazole-5-carbonitrileHCID 57917036—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-1e8bf93b39744627b3e3106a11cf7810
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)