6-(4-oxocyclohexyl)-1,3-benzoxazol-2(3H)-one → 6-(trans-4-[3-(3,5-difluorophenyl)propylamino]cyclohexyl}-3H-benzoxazol-2-one
Reaction equation
[CH:13]1([c:20]2[cH:21][c:22]3[c:23]([nH:24][c:25](=[O:27])[o:26]3)[cH:28][cH:29]2)[CH2:14][CH2:15][C:16](=[O:19])[CH2:17][CH2:18]1.[F:1][c:2]1[cH:3][c:4]([CH2:9][CH2:10][CH2:11][NH2:12])[cH:5][c:6]([F:8])[cH:7]1>>[F:1][c:2]1[cH:3][c:4]([CH2:9][CH2:10][CH2:11][NH:12][CH:16]2[CH2:15][CH2:14][CH:13]([c:20]3[cH:21][c:22]4[c:23]([nH:24][c:25](=[O:27])[o:26]4)[cH:28][cH:29]3)[CH2:18][CH2:17]2)[cH:5][c:6]([F:8])[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-d0b2bfdafe0949f68991d960429c842d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…