Dichloromethane → 4-[5-(4-Aminothieno[2,3-d]pyrimidin-6-yl)-1-methyl-1H-imidazol-4-yl]phenol

HRID 2148253Notes

Reaction equation

HRID 2148253 reaction equation
[B:1]([Br:2])([Br:3])[Br:4].[CH3:5][O:6][c:7]1[cH:8][cH:9][c:10](-[c:13]2[n:14][cH:15][n:16]([CH3:28])[c:17]2-[c:18]2[cH:19][c:20]3[c:21]([n:22][cH:23][n:24][c:25]3[NH2:26])[s:27]2)[cH:11][cH:12]1.[Cl:29][CH2:30][Cl:31]>>[OH:6][c:7]1[cH:8][cH:9][c:10](-[c:13]2[n:14][cH:15][n:16]([CH3:28])[c:17]2-[c:18]2[cH:19][c:20]3[c:21]([n:22][cH:23][n:24][c:25]3[NH2:26])[s:27]2)[cH:11][cH:12]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 25134Boron tribromideHCID 691973206-[4-(4-Methoxyphenyl)-1-methyl-1H-imidazol-5-yl]thieno[2,3-d]pyrimidin-4-amine

Product 1

HCID 102456254-[5-(4-Aminothieno[2,3-d]pyrimidin-6-yl)-1-methyl-1H-imidazol-4-yl]phenol

Sources & evidence

ORD record
ord-6391a6dfce5845d7b8223c58b31b8313
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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