1-(3-Methyl-1,2,4-thiadiazol-5-yl)piperidin-4-one → [8-(3-Dimethylamino-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[1-(3-methyl-[1,2,4]thiadiazol-5-yl)-piperidin-4-yl]-amine

HRID 2148279Notes

Reaction equation

HRID 2148279 reaction equation
[CH3:14][N:15]([c:16]1[cH:17][c:18](-[c:22]2[c:23]3[n:24]([cH:25][cH:26][cH:27]2)[n:28][c:29]([NH2:31])[n:30]3)[cH:19][cH:20][cH:21]1)[CH3:32].[CH3:1][c:2]1[n:3][s:4][c:5]([N:7]2[CH2:8][CH2:9][C:10](=[O:13])[CH2:11][CH2:12]2)[n:6]1>>[CH3:1][c:2]1[n:3][s:4][c:5]([N:7]2[CH2:8][CH2:9][CH:10]([NH:31][c:29]3[n:28][n:24]4[c:23]([c:22](-[c:18]5[cH:17][c:16]([N:15]([CH3:14])[CH3:32])[cH:21][cH:20][cH:19]5)[cH:27][cH:26][cH:25]4)[n:30]3)[CH2:11][CH2:12]2)[n:6]1

Participants

3

Reactant 2

HCID 592585101-(3-Methyl-1,2,4-thiadiazol-5-yl)piperidin-4-oneHCID 673425328-(3-Dimethylamino-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine

Product 1

HCID 58397862[8-(3-Dimethylamino-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[1-(3-methyl-[1,2,4]thiadiazol-5-yl)-piperidin-4-yl]-amine

Sources & evidence

ORD record
ord-e0d4604bfed440a8b86958275ebaf713
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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