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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2148521Generated: October 31, 2026

Dichloromethane → N-(4-{4-[7-(4-cyano-3-trifluoromethylphenyl)-8-oxo-6-thioxo-5,7-diaza-spiro[3,4]oct-5-yl]phenyl}-butanoyl)-methanesulfonamide

https://huagongshe.com/reaction/2148521

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
Reactant4-(Dimethylamino)pyridineHCID 14284—
ReactantMethanesulfonamideHCID 72879—
Reactant2,4,6-Trichlorobenzoyl chlorideHCID 2733703—
Reactant4-(4-(7-(4-Cyano-3-(trifluoromethyl)phenyl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)phenyl)butanoic acidHCID 86609866—
ProductN-(4-{4-[7-(4-cyano-3-trifluoromethylphenyl)-8-oxo-6-thioxo-5,7-diaza-spiro[3,4]oct-5-yl]phenyl}-butanoyl)-methanesulfonamideHCID 86643201—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-b57b13618782495f9a677ea8ff0453cb
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)