Bromide ion → tert-Butyl 3-hydroxy-3-methylpyrrolidine-1-carboxylate

HRID 2148549Notes

Reaction equation

HRID 2148549 reaction equation
[Br-:14].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][C:10](=[O:13])[CH2:11][CH2:12]1.[CH3:15][Mg+:16].[CH3:17][CH2:18][O:19][CH2:20][CH3:21]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][C:10]([OH:13])([CH3:15])[CH2:11][CH2:12]1

Participants

5

Reactant 4

HCID 259Bromide ionHCID 3283Diethyl EtherHCID 471360Tert-butyl 3-oxopyrrolidine-1-carboxylateHCID 178477777HCID 178477777, compound

Product 1

HCID 22951485tert-Butyl 3-hydroxy-3-methylpyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-e9b3c540ff64402caaa6ab5a897ac8eb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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