1-Methyl-5-[2-(phenoxymethyl)pyrrolidin-1-yl]sulfonylindole-2,3-dione → 1-[(4-Fluorophenyl)methyl]-5-[2-(phenoxymethyl)azetidin-1-yl]sulfonylindole-2,3-dione
Reaction equation
[CH3:1][N:2]1[c:3]2[c:4]([cH:5][c:6]([S:7]([N:8]3[CH2:9][CH2:10][CH2:11][CH:12]3[CH2:13][O:14][c:15]3[cH:16][cH:17][cH:18][cH:19][cH:20]3)(=[O:21])=[O:22])[cH:23][cH:24]2)[C:25](=[O:26])[C:27]1=[O:28].[F:55][c:56]1[cH:57][cH:58][c:59]([CH2:60][Br:61])[cH:62][cH:63]1.[O:29]([c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1)[CH2:36][CH:37]1[N:38]([S:41](=[O:42])(=[O:43])[c:44]2[cH:45][c:46]3[c:50]([cH:51][cH:52]2)[NH:49][C:48](=[O:53])[C:47]3=[O:54])[CH2:39][CH2:40]1>>[O:29]([c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1)[CH2:36][CH:37]1[N:38]([S:41](=[O:42])(=[O:43])[c:44]2[cH:45][c:46]3[c:50]([cH:51][cH:52]2)[N:49]([CH2:60][c:59]2[cH:58][cH:57][c:56]([F:55])[cH:63][cH:62]2)[C:48](=[O:53])[C:47]3=[O:54])[CH2:39][CH2:40]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-67822385c1a343089bdff682b9e6f491
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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