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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2149007Generated: October 26, 2026

Citric Acid → Methyl 5-[tert-butyl(dimethyl)silyl]oxy-2-hydroxypentanoate

https://huagongshe.com/reaction/2149007

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCitric AcidHCID 311—
ReactantDiethyl EtherHCID 3283—
ReactantAcetonitrileHCID 6342—
ReactantDiisopropylamineHCID 7912—
ReactantTetrahydrofuranHCID 8028—
ReactantHydrogen iodideHCID 24841—
ReactantMethyl 5-(tert-butyl-dimethylsilyl)oxypentanoateHCID 11139432—
ReactantButyllithiumHCID 178418339—
ReactantHCID 178418778HCID 178418778—
ReactantHCID 178524002HCID 178524002—
ProductMethyl 5-[tert-butyl(dimethyl)silyl]oxy-2-hydroxypentanoateHCID 14321488—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-c4e621f823f44404bab4844b3697f380
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)