Ethyl 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanecarboxylate → 1-{4'-[4-(1-Hydroxy-2-phenethyloxy-ethyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester

HRID 2149262Notes

Reaction equation

HRID 2149262 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([CH:14]([CH2:15][O:16][CH2:17][CH2:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[OH:25])[c:10]([CH3:13])[n:11][o:12]2)[cH:6][cH:7]1.[CH2:26]([CH3:27])[O:28][C:29](=[O:30])[C:31]1([c:34]2[cH:35][cH:36][c:37]([B:40]3[O:41][C:42]([CH3:43])([CH3:44])[C:45]([CH3:46])([CH3:47])[O:48]3)[cH:38][cH:39]2)[CH2:32][CH2:33]1>>[c:2]1(-[c:37]2[cH:36][cH:35][c:34]([C:31]3([C:29]([O:28][CH2:26][CH3:27])=[O:30])[CH2:32][CH2:33]3)[cH:39][cH:38]2)[cH:3][cH:4][c:5](-[c:8]2[c:9]([CH:14]([CH2:15][O:16][CH2:17][CH2:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[OH:25])[c:10]([CH3:13])[n:11][o:12]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 53217182Ethyl 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanecarboxylateHCID 665772101-[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-2-phenethyloxy-ethanol

Product 1

HCID 665773951-{4'-[4-(1-Hydroxy-2-phenethyloxy-ethyl)-3-methyl-isoxazol-5-yl]-biphenyl-4-yl}-cyclopropanecarboxylic acid ethyl ester

Sources & evidence

ORD record
ord-53a7fd4f7c8c4b98b863528fe2e1df13
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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