1-(3-Aminopropyl)-4-(2-methoxyphenyl)piperazine → 6-(2,6-Dichlorophenyl]-2-[3-[4-(2-methoxyphenyl)-piperazin-1-yl]-propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one

HRID 2149316Notes

Reaction equation

HRID 2149316 reaction equation
[Cl:1][c:2]1[c:3](-[c:9]2[cH:10][c:11]3[c:12]([n:13][c:14]([S:17][CH3:18])[n:15][cH:16]3)[n:19]([CH3:22])[c:20]2=[O:21])[c:4]([Cl:8])[cH:5][cH:6][cH:7]1.[NH2:23][CH2:24][CH2:25][CH2:26][N:27]1[CH2:28][CH2:29][N:30]([c:33]2[c:34]([O:39][CH3:40])[cH:35][cH:36][cH:37][cH:38]2)[CH2:31][CH2:32]1>>[Cl:1][c:2]1[c:3](-[c:9]2[cH:10][c:11]3[c:12]([n:13][c:14]([NH:23][CH2:24][CH2:25][CH2:26][N:27]4[CH2:28][CH2:29][N:30]([c:33]5[c:34]([O:39][CH3:40])[cH:35][cH:36][cH:37][cH:38]5)[CH2:31][CH2:32]4)[n:15][cH:16]3)[n:19]([CH3:22])[c:20]2=[O:21])[c:4]([Cl:8])[cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 104672591-(3-Aminopropyl)-4-(2-methoxyphenyl)piperazineHCID 107367016-(2,6-Dichlorophenyl)-8-methyl-2-(methylthio)pyrido[2,3-d]pyrimidin-7(8H)-one

Product 1

HCID 116784236-(2,6-Dichlorophenyl]-2-[3-[4-(2-methoxyphenyl)-piperazin-1-yl]-propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one

Sources & evidence

ORD record
ord-ea28fd26d25e446d97074a1993850b5b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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