4-Chloro-2,5-dimethoxyaniline → N2-(4-chloro-2,5-dimethoxyphenyl)-5-fluoro-N4-(3-hydroxyphenyl)-2,4-pyrimidinediamine

HRID 2149324Notes

Reaction equation

HRID 2149324 reaction equation
[Cl:17][c:18]1[cH:19][c:20]([O:27][CH3:28])[c:21]([NH2:22])[cH:23][c:24]1[O:25][CH3:26].[Cl:1][c:2]1[n:3][cH:4][c:5]([F:16])[c:6]([NH:8][c:9]2[cH:10][c:11]([OH:15])[cH:12][cH:13][cH:14]2)[n:7]1>>[c:2]1([NH:22][c:21]2[c:20]([O:27][CH3:28])[cH:19][c:18]([Cl:17])[c:24]([O:25][CH3:26])[cH:23]2)[n:3][cH:4][c:5]([F:16])[c:6]([NH:8][c:9]2[cH:10][c:11]([OH:15])[cH:12][cH:13][cH:14]2)[n:7]1

Participants

3

Reactant 2

HCID 228334-Chloro-2,5-dimethoxyanilineHCID 220604512-chloro-5-fluoro-N-(3-hydroxyphenyl)-4-pyrimidineamine

Product 1

HCID 22060583N2-(4-chloro-2,5-dimethoxyphenyl)-5-fluoro-N4-(3-hydroxyphenyl)-2,4-pyrimidinediamine

Sources & evidence

ORD record
ord-dbcae8c37dcf4583a8d4386a4dbcd9d0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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