4-[3-(Trifluoromethyl)phenyl]butan-2-one → [5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-[1-methyl-3-(3-trifluoromethyl-phenyl)-propyl]-amine

HRID 2149479Notes

Reaction equation

HRID 2149479 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([NH2:14])[c:10]([CH3:13])[n:11][o:12]2)[cH:6][cH:7]1.[F:15][C:16]([c:17]1[cH:18][c:19]([CH2:23][CH2:24][C:25]([CH3:26])=[O:27])[cH:20][cH:21][cH:22]1)([F:28])[F:29]>>[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9]([NH:14][CH:25]([CH2:24][CH2:23][c:19]3[cH:18][c:17]([C:16]([F:15])([F:28])[F:29])[cH:22][cH:21][cH:20]3)[CH3:26])[c:10]([CH3:13])[n:11][o:12]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 133390594-[3-(Trifluoromethyl)phenyl]butan-2-oneHCID 582185375-(4-Bromophenyl)-3-methylisoxazol-4-amine

Product 1

HCID 66577310[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-[1-methyl-3-(3-trifluoromethyl-phenyl)-propyl]-amine

Sources & evidence

ORD record
ord-3ef76b60070b4ae995b669be9f379e98
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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