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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2149639Generated: October 26, 2026

Methanol → 3,4-difluoro-2-[2-fluoro-4-(3-hydroxy-3-methyl-1-butynyl)anilino]-N-(2-hydroxyethoxy)benzamide

https://huagongshe.com/reaction/2149639

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantDiethyl EtherHCID 3283—
Reactant2-Methyl-3-butyn-2-olHCID 8258—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)benzamideHCID 9803891—
Product3,4-difluoro-2-[2-fluoro-4-(3-hydroxy-3-methyl-1-butynyl)anilino]-N-(2-hydroxyethoxy)benzamideHCID 10287651—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-6805b97f5b47410ba4159b563bc0b243
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)