3,3,3-Trifluoropropylamine → 2-fluoro-2-methyl-N-[6-oxo-5-(2-phenylmethoxyethyl)-7H-benzo[d][1]benzazepin-7-yl]-N'-(3,3,3-trifluoropropyl)propanediamide
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][CH2:9][CH2:10][N:11]1[c:12]2[c:13]([cH:32][cH:33][cH:34][cH:35]2)-[c:14]2[c:15]([cH:28][cH:29][cH:30][cH:31]2)[CH:16]([NH:19][C:20]([C:21]([C:22](=[O:23])[OH:24])([CH3:25])[F:26])=[O:27])[C:17]1=[O:18].[F:36][C:37]([CH2:38][CH2:39][NH2:40])([F:41])[F:42]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][CH2:9][CH2:10][N:11]1[c:12]2[c:13]([cH:32][cH:33][cH:34][cH:35]2)-[c:14]2[c:15]([cH:28][cH:29][cH:30][cH:31]2)[CH:16]([NH:19][C:20]([C:21]([C:22](=[O:23])[NH:40][CH2:39][CH2:38][C:37]([F:36])([F:41])[F:42])([CH3:25])[F:26])=[O:27])[C:17]1=[O:18]Participants
3
Sources & evidence
- ORD record
- ord-9063aebd834f4cdb803b7ea7dfb6ca2d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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