Sodium ion → (4,4-Difluoropiperidin-1-yl)-[5-[3-(2-methylpyrrolidin-1-yl)propoxy]-1-methylsulfonylpyrrolo[2,3-b]pyridin-2-yl]methanone

HRID 2149691Notes

Reaction equation

HRID 2149691 reaction equation
[CH3:32][S:33]([Cl:34])(=[O:35])=[O:36].[F:1][C:2]1([F:29])[CH2:3][CH2:4][N:5]([C:8](=[O:9])[c:10]2[cH:11][c:12]3[c:13]([n:14][cH:15][c:16]([O:18][CH2:19][CH2:20][CH2:21][N:22]4[CH:23]([CH3:27])[CH2:24][CH2:25][CH2:26]4)[cH:17]3)[nH:28]2)[CH2:6][CH2:7]1.[H-:30].[Na+:31]>>[F:1][C:2]1([F:29])[CH2:3][CH2:4][N:5]([C:8](=[O:9])[c:10]2[cH:11][c:12]3[c:13]([n:14][cH:15][c:16]([O:18][CH2:19][CH2:20][CH2:21][N:22]4[CH:23]([CH3:27])[CH2:24][CH2:25][CH2:26]4)[cH:17]3)[n:28]2[S:33]([CH3:32])(=[O:35])=[O:36])[CH2:6][CH2:7]1

Participants

5

Reactant 4

HCID 923Sodium ionHCID 31297Methanesulfonyl chlorideHCID 166653HydrideHCID 68422402(4,4-difluoropiperidin-1-yl)-[5-[3-(2-methylpyrrolidin-1-yl)propoxy]-1H-pyrrolo[2,3-b]pyridin-2-yl]methanone

Product 1

HCID 68423476(4,4-Difluoropiperidin-1-yl)-[5-[3-(2-methylpyrrolidin-1-yl)propoxy]-1-methylsulfonylpyrrolo[2,3-b]pyridin-2-yl]methanone

Sources & evidence

ORD record
ord-6b3bb91223ee4bb5b8548e198e0a8522
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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